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Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. 44% of reviewers reported a positive effect, while 32% reported a negative effect. Examples of SNRI medications include duloxetine (Cymbalta), venlafaxine (Effexor XR), desvenlafaxine (Pristiq) and levomilnacipran (Fetzima).. 9 kg 20, 26, 27 ), lurasidone (0. 3 kg (up to 11%) Paxil: Common (1% to 10% of users): Decreased appetite, increased appetite, increases in cholesterol levels, weight gain, weight loss. “A newer antidepressant, vortioxetine (Trintellix) may also have less weight gain risk. ” Bupropion (Wellbutrin), amitriptyline (Elavil), and nortriptyline (Pamelor) are also shown to have less of. 8 out of 10 from a total of 407 ratings on Drugs. 9 kg 20, 26, 28 ), ziprasidone (−1. Paroxetine Alternatives Compared Paroxetine Trintellix (vortioxetine) Bupropion Prescription only Paroxetine may be used in the treatment of depression or anxiety disorders. Trintellix: Frequency not reported: Weight gain (This is because post. The same can be said for side effects Effexor has an average rating of 5. 21 hours 66 hours 30 hours CSA Schedule ** View glossary of terms N. Serotonin and norepinephrine reuptake inhibitors (SNRIs). Taking paroxetine with other medications such as tramadol that also more Prescription only. 47% of reviewers reported a positive effect, while 33% reported a negative effect SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro). Vortioxetine has an average rating of 6. Common side effects include a headache and nausea. 0 out of 10 from a total of 1378 ratings on Drugs. 3 kg (up to 28%), weight gain greater than 2. Wellbutrin: Very common (10% or more of users): Weight loss greater than 2. Because newer drugs tend to have fewer side effects, those two aren’t prescribed as frequently Conversely, the use of paliperidone (−1. Amitriptyline and nortriptyline are older drugs. Bupropion was associated with the least amount of weight gain, close to none. 1 kg 13, 16, 20) and aripiprazole (−1. The only difference in Celexa vs Paxil comparison is In terms of their side effects, Paroxetine side effects are more prominent compared to Celexa, especially the weight gain adverse reactions.